The La Liga and Champions League winning coach confirmed that the pair would be given their first starts since joining the club over the summer.
“Arda and Vidal will both be involved on Wednesday,” Luis Enrique said at a news conference.
Turan joined Barcelona last summer but due to the FIFA transfer ban the club has been unable to register him until the turn of the year.
The Turkish international has received the number 7 shirt number which was previously worn by Pedro.
The 28-year-old has been able to maintain a high level of match fitness due to playing regularly for the Turkish national team playing a key role in the Crescent-Stars reaching the European Championships.
Barcelona squad: Marc-Andre ter Stegen, Jordi Masip, Gerard Pique, Ivan Rakitic, Sergio Busquets, Dani Alves, Arda Turan, Andres Iniesta, Luis Suarez, Lionel Messi, Neymar, Javier Mascherano, Marc Bartra, Munir El Haddadi, Jordi Alba, Aleix Vidal, Thomas Vermaelen, Jeremy Mathieu.