Ozil and Sanchez have only started one other league game this season and that was the 3-1 win over Watford.
The Germany international of Turkish origin has two goals and an assist in all competitions for the Gunners this season.
In other Arsenal team news head coach Arsene Wenger gave an answer to the question on everybody’s lips – will Petr Cech return or will David Ospina keep his place in goal following an incredible display against PSG in the Champions League.
“Cech will be back,” Wenger said in his pre-match press conference. “I have two world class goalkeepers and for the day I chose Ospina and he had an outstanding game.
“You cannot keep it where one of them does not get a game. You have to give them games in big competitions.”
The Gunners could be without Theo Walcott who faces a late fitness test but Olivier Giroud should be available after featuring against PSG mid-week – and getting himself sent off.
Aaron Ramsey, Gabriel, Carl Jenkinson, Danny Welbeck and Per Mertesacker are all out sidelined for the Gunners.
Hull City have six players out injured including, Allan McGregor, Michael Dawson, Moses Adubajo, Alex Bruce, Greg Luer and Brian Lenihan.
Tigers caretaker manager Mike Phelan confirmed former Norwich striker Mbokani is match ready while club record signing Ryan Mason and Will Keane are expected to start after making their debuts off the bench in the 1-1 dray against Burnley last week. Fellow summer signings Markus Henriksen, James Weir and David Marshall could all feature.
Full team squads:
Hull’s team from: Jakupovic, Marshall, Elmohamady, Davies, Robertson, Livermore, Clucas, Maloney, Snodgrass, Diomande, Keane, Huddlestone, Meyler, Mason, Hernandez, Maguire, Henriksen, Weir, Mbokani.
Arsenal team from: Cech, Ospina, Macey, Martinez, Debuchy, Bellerin, Jenkinson, Koscielny, Mustafi, Holding, Gibbs, Monreal, Elneny, Coquelin, Cazorla, Xhaka, Oxlade-Chamberlain, Walcott, Iwobi, Ozil, Sanchez, Giroud, Perez, Sanogo
Guide to pronouncing Mesut Ozil