The Gunners picked up a hard earned point away to PSG in their opening game of the competition and sit at the top of Group A.
Wenger does have a decision to make in midfield following the injury to Francis Coquelin. Summer signing Granit Xhaka is expected to step in, following a string of impressive performances since making the move from Borussia Mönchengladbach.
Olivier Giroud is also ruled out after being sent off in the Arsenal’s first Group A game against PSG.
The Chile international Alexis Sanchez is expected to retain his place up-front following an impressive performance against Chelsea on Saturday.
Arsenal go into the game on the back of three consecutive wins in the Premier League including a 3-0 victory over rivals Chelsea.
Arsenal v Basel
Kick-Off: 19:45 (GMT)
Stadium: Emirates Stadium
Arsenal probable lineup: Cech; Bellerin, Mustafi, Koscielny, Monreal; Xhaka, Cazorla; Alexis, Ozil, Walcott; Perez
FC Basel probable lineup: Vaclik; Lang, Suchy, Balanta, Traore; Xhaka; Bjanrason, Zuffi, Delgado, Steffen; Janko