The Gunners will move into first place with a win over the Toffees but City could take their spot at the top of the table back with a win against Manchester United in the derby tomorrow.
Arsenal boss Arsene Wenger will start with Mesut Özil who he has waxed lyrical over the past few days.
The north London based side will be in high spirits after beating Bayern Muncih 2-0 in the Champions League midweek. Özil scored the second goal against the German giants – his second consecutive goal in big games.
Arsenal will be without Aaron Ramsey, Jack Wilshere, Danny Welbeck and Tomas Rosicky against Everton.
Arsenal v Everton
Kick-Off: 17:00 GMT
Arsenal confirmed starting lineup: Cech; Bellerin, Gabriel, Koscielny, Monreal; Coquelin, Chamberlain; Cazorla, Ozil, Sanchez; Giroud
Subs: Macey, Debuchy, Gibbs, Chambers, Flamini, Campbell, Walcott
Everton confirmed starting lineup: Howard, Coleman, Galloway, Jagielka, Stones, Barry, McCarthy, Lennon, Deulofeu, Barkley, Lukaku.a
Subs: Joel, Kone, Mirallas, Naismith, Cleverley, Osman, Funes Mori