Arsenal welcome Watford to the Emirates knowing that they must win in order to stay in the title race.
The Gunners are currently in third place 11 points behind leaders Leicester City but do have a game in hand.
North London rivals Tottenham are currently in second six points clear of Arenal.
Arsenal manager Arsene Wenger will be without Jack Wilshere, Tomas Rosicky, Alex Oxlade-Chamberlain, Santi Cazorla, Mathieu Flamini and Aaron Ramsey all of whom are injured going into the game.
The World Cup winner starred in the 3-2 defeat to England and the 4-1 win over Germany last week so fatigue could be an issue but he will start today.
Arsenal v Watford
Kick-Off: 15:00 GMT
Arsenal confirmed starting lineup:
Ospina; Bellerin, Gabriel, Koscielny, Monreal; Elneny, Coquelin, Sanchez, Ozil, Welbeck; Iwobi
Subs: Cech, Giroud, Gibbs, Mertesacker, Walcott, Campbell
Manager: Arsene Wenger
Watford confirmed starting lineup:
Gomes (GK); Nyom, Prödl, Cathcart, Ake; Capoue, Watson, Suarez; Abdi, Deeney (c); Ighalo
Subs: Pantilimon (GK), Britos, Guedioura, Anya, Berghuis, Jurado, Amrabat.
Manager: Quique Sánchez Flores