The Catalan giants recorded a hard fought 2-1 win over Atletico in the first leg and know a draw will see them qualify to the semi finals.
Arda Turan has come under criticism in recent weeks for his performances. The Turkish international is expected to start on the bench as Rakitic returns to the starting line-up.
Turan started in Barcelona’s 1-0 defeat at the hands of Real Sociedad over the weekend.
The 29-year-old has two goals and four assists in the 17 games he has featured in this season and still has another five years remaining on his contract.
Atletico Madrid v Barcelona
Kick-Off: 19:45 (GMT)
Stadium: Vicente Calderón
Atletico Madrid probable starting line-up: Oblak, Juanfran, Godín, Lucas, Filipe Luís, Augusto, Saúl, Koke, Gabi, Carrasco, Griezmann
Barcelona probable starting line-up: Ter Stegen; Alves, Piqué, Mascherano, Alba; Busquets, Rakitic, Iniesta; Messi, Suárez, Neymar