The Black Eagles are currently first in the Süper Lig but will have beat an in form Trabzonspor to stay at the top.
The Black Sea Storm have won their last six consecutive league games including a victory over Galatasaray.
Beşiktaş did however, beat Trabzonspor 3-0 the last time the two sides met.
The Eagles will be without Necip Uysal and Serdar Kurtuluş due to suspension.
Turkish international defender Ersan Gülüm is also expected to miss the game with injury.
Demba Ba and winger Kerim Frei will face suspension against Gaziantepspor next week if they pick up a yellow card in the Trabzonspor game.
The full Beşiktaş squad is as follows:
Cenk Gönen, Günay Güvenç, Veysel Sapan, Ersan Adem Gülüm, Pedro Franco, Tomas Sivok, Alexander Milosevic, Atınç Nukan, Ramon Motta, Daniel Opare, Atiba Hutchinson, Oğuzhan Özyakup, Tolgay Arslan, Kerim Frei, Gökhan Töre, Olcay Şahan, Jose Sosa, Cenk Tosun, Mustafa Pektemek, Demba Ba