The Gunners beat Chelsea the last time the two sides met in the Community Shield at the start of the season.
Mesut Özil started for Arsenal in that game and is expected to be in the starting XI today as well despite a disappointing performance against Dynamo Zagreb midweek.
The North London based club suffered a surprise defeat against the Croatian giants in their opening Champions League group game.
Chelsea had no such problems as they swept Maccabi aside but it has been a different story in the league as the Blues have only managed to pick up four points from five games and are currently in 17th place.
Jose Mourinho’s side will be without the injured Willian while Pedro and Radamel Falcao are also doubts.
Chelsea v Arsenal
Stadium: Stamford Bridge
Chelsea possible starting lineup:
Begovic; Ivanovic, Terry, Cahill, Azpilicueta; Matic, Fabregas; Ramires, Oscar, Hazard; Costa
Arsenal possible starting lineup:
Cech; Bellerin, Gabriel, Koscielny, Monreal; Coquelin, Cazorla, Ramsey, Ozil, Sanchez; Walcott