The Bundesliga giants host the Red’s at the Signal Iduna Park in the Europa League, kick-off is at 20:05.
Emre Can is expected to be included in Liverpool’s midfield while Ilkay Gundogan will face a late fitness test after returning to first team training.
Dortmund skipper Mats Hummels and centre back Sokratis Papastathopoulos are also expected to returned after sitting out Saturday’s win over Werder Bremen.
Gundogan has seven assists and three goals in 36 appearances for Dortmund this season.
Dortmund v Liverpool
Kick-Off: 20:05 (GMT)
Stadium: Signal Iduna Park
Dortmund probable line-up: Burki; Piszczek, Ginter, Hummels, Schmelzer; Gundogan, Castro, Durm, Mkhitaryan, Reus; Aubameyang
Liverpool probable line-up: Mignolet; Clyne, Lovren, Sakho, Moreno; Henderson, Can; Lallana, Firmino, Coutinho; Sturridge