UEFA permit Europa League sides in the Round of 32 stage to make up to three changes to their original squad submission.
Emre Can has kept his place in the squad but Adam Bogdan, Joe Gomez and Danny Ings have all been removed.
Meanwhile Steven Caulker, Joao Carlos Teixeira and Danny Ward have all been added to the squad.
Jon Flanagan and Jose Enrique have been left out of the squad submission.
Steven Caulker, Joao Carlos Teixeira, Danny Ward
Adam Bogdan, Joe Gomez, Danny Ings
Liverpool Europa League Squad: Simon Mignolet, Danny Ward, Nathaniel Clyne, Steven Caulker, Kolo Toure, Dejan Lovren, Alberto Moreno, Mamadou Sakho, Martin Skrtel, Lucas Leiva, Jordan Henderson, James Milner, Emre Can, Joe Allen, Philippe Coutinho, Adam Lallana, Roberto Firmino, Divock Origi, Joao Teixeira, Daniel Sturridge, Christian Benteke