The Lions will be without Hamit Altıntop, Sinan Gumus, Wesley Sneijder, Hakan Balta, Sabri and captain Selcuk inn due to injury while Olcan Adin is suspended.
EsEs are in dreadful form without a win in their last five games and sit rock bottom at the foot of the table.
Eskisehirspor will also be desperate for a win and Galatasaray could struggle without talisman Sneijder and captain Selcuk Inan.
Galatasaray still have more than enough attacking options to trouble the shaky EsEs backline but the Lions have plenty of defensive problems themselves to worry about.
Predicting: Over 2.5 goals
ESKİŞEHİRSPOR – GALATASARAY
Stadium: Eskişehir Atatürk
Referee: Cüneyt Çakır
Kick-Off: 19:00 (Local Time)
Eskisehirspor: Boffin, Kamil, Junior, Figueras, İshak, Kıvanç, Hadzic, Emre Güral, Nadir, Engin, Meye,
Manager: Samet Aybaba
Galatasaray: Muslera, Linnesi Chedjou, Semih , Carole, Bilal, Donk, Emre, Yasin, Umut , Podolski
Manager: Jan Olde Riekerink,