Eskisehirspor are still struggling for form following the arrival of Michael Skibbe in place of Ertuğrul Sağlam. EsEs have lost two and drawn one of their last three games and in 14th place in the league with 17 points.
Diego Angelo, Kaan Kanak, Birol Parlak, Funes Mori, Mirkan Aydin and Ömer Şişmanoğlu are doubts for the Galatasaray clash while Ibrahim Sissoko will miss the game due to a suspension.
Galatasaray slipped up last weekend and cant afford any more mistakes if they are to keep up with the leading pack. Hamza Hamzaoglu will be able to call upon captain Selcuk Inan after serving a one match suspension. Top scorer Burak Yilmaz is also set to make a return.
Hamit Altintop Semih Kaya Goran Pandev, Aydin Yilmaz have been ruled out through injury.
Galatasaray were fortunate to get away with a draw against Bursaspor last weekend but will be strengthened with the return of Selcuk in midfield. Eskisehirspor have been poor this season and will struggle to stop the Istanbul Giants from leaving with all three points.