Beşiktaş take on Skenderbeu needing a win that could ensure direct qualification to the Europa League Round of 32 depending on the other results in the group.
Black Eagles manager Şenol Güneş has a full strength side to chose from other than Gökhan Töre and long term absentees Veli Kavlak and Tolgay Arslan.
Güneş will however, make a number of changes to the side that beat Sivasspor last week to stay first in the Turkish Super League.
Quaresma has been dropped for former Fulham youngster Kerim Frie and Cenk Tosun will start ahead of the in form Mario Gomez.
BEŞİKTAŞ – SKENDERBEU
Stadium: Atatürk Olimpiyat
Referee: Pawel Gil (Polonya)
Kick-Off: 18:00 GMT
BEŞİKTAŞ: Tolga, Beck, Rhodolfo, Ersan, İsmail, Gökhan,Necip, Atiba, Oğuzhan, Kerim, Cenk
MANAGER: Şenol Güneş
SKENDERBEU: Shehi, Osmani, Jashanica, Ademir, Abazi, Berisha, Junior, Progni, Esquerdinha, Olayinka, Salihi
MANAGER: Mirel Josa