Everton are bound to be full of confidence after knocking Chelsea out of the FA Cup to progress to the semi-finals.
The Toffees will be without the suspended Gareth Barry but Kevin Mirallas returns after serving a one-match ban.
Arsenal’s injury woes continue to mount up as Mathieu Flamini picked up an injury against Barcelona.
Jack Wilshere, Santi Cazorla, Petr Cech and Aaron Ramsey are also all sidelined with injury.
Mesut Ozil is however, expected to start and has 19 assists in the league this season.
Everton v Arsenal
Stadium: Goodison Park
Kick-Off: 12:45 GMT
Everton Predicted XI: Robles; Baines, Coleman, Funes Mori, Jagielka; Besic, McCarthy; Lennon, Barkley, Mirallas; Lukaku.
Arsenal Predicted XI: Ospina; Monreal, Koscielny, Gabriel, Bellerin; Elneny, Coquelin; Ozil, Sanchez, Campbell; Giroud
Manager: Arsene Wenger