The Yellow Canaries will be without Robin van Persie against United despite the striker being in excellent form.
Van Persie had contributed directly to 13 goals in his last 12 league games going into the game – nine goals and four assists. The 33-year-old has however, been included on the bench going into the game.
Moussa Sow will be replacing Van Persie upfront with Jeremain Lens and Volkan Sen on the wings.
In other Fenerbahce team news Mehmet Topal and Josef De Souza will shield the defence in midfield while Alper Potuk will play a box to box role.
The defence will be comprised of Simon Kjaer and Martin Skrtel as centre-backs while Hasan Ali and Sener Ozbayrakli will start as full-backs.
Fenerbahce starting line-up: Volkan, Hasan Ali, Skrtel, Kjaer, Sener, Mehmet Topal, Josef De Souza, Alper Potuk, Jeremain Lens, Volkan Sen, Moussa Sow