Galatasaray go into the game without their captain Selçuk Inan and first choice striker Burak Yılmaz who are both injured.
The Istanbul based club are also without a manager after Hamza Hamzaoğlu was sacked last week despite winning three trophies within six months.
Goalkeeping coach Claudio Taffarel is expected to take charge of the team going into the clash but there could be last minute changes as Mustafa Denizli is expected to take over at any moment.
Atletico Madrid v Galatasaray
Kick-Off: 19:45 GMT
Stadium: Vicente Calderon
Atlético: Oblak, Gamez, Godin, Giménez, Filipe, Gabi, Tiago, Koke, Carrasco, Griezmann, Torres
Manager: Diego Simeone
Galatasaray: Muslera, Denayer, Semih, Chedjou, Hakan Balta, Bilal, Jem Paul, Sabri, Yasin, Sneijder, Podolski
Manager: Claudio Taffarel