Galatasaray have the chance to move into first place with a win against Gaziantepspor following Fenerbahçe’s 1-1 draw against Eskişehirspor.
The Istanbul giants will be desperate to get their title challenge back on track following a 2-1 loss to Trabzonspor last week.
The Lions are currently third, but sit just one point behind league leaders Fenerbahçe with a game in hand.
Gaziantepspor are relatively safe and almost certain to avoid relegation this season.
Galatasaray will be without the suspended Wesley Sneijder but Felipe Melo will make his return and start in midfield.
Emre Çolak will replace Sneijder and Olcan Adın will also make a rare start.
Galatasaray – Gaziantepspor
STADIUM: Türk Telekom Arena
REFEREE: Mete Kalkavan
GALATASARAY: Muslera, Sabri, Chedjou, Hakan, Telles, Melo, Selçuk, Emre, Olcan, Umut, Burak Yılmaz
MANAGER: Hamza Hamzaoğlu
GAZİANTEPSPOR: Eray, Elyasa, Arokoyo, Şenol, Chico, Barış, Chibuike, Erdem, Mustafa, Muhammet, Luis Leal
MANAGER: Okan Buruk