The Serbian international is currently out injured but is expected to return to training this week and play in the Istanbul derby against Besiktas.
Markovic has been in good form for Fenerbahce when fit but he has had injury problems throughout the season.
Fenerbahce boss Vitor Pereira will rest Robin van Persie today and start with Fernandao up-front. Former Manchester United winger Luis Nani will start as will mid-week Europa League hero Josef de Souza who bagged a brace in the 2-0 win over Lokomotiv Moscow.
The Istanbul giants have won eight of the last ten meetings with Bursaspor in all competitions.
Bursaspor – Fenerbahce
Stadium: Bursa Büyükşehir Belediye Stadı
Referee: Mete Kalkavan
Kick-Off: 17:00 GMT
Bursaspor: Harun, Hosagai, Şamil, Sivok, Aziz Behich, Faty, Bekir, Deniz, Batalla, Sercan, Neci
Manager: Hamza Hamzoğlu
Fenerbahce: Volkan, Gökhan, Alves, Kjaer, Caner, M.Topal, Josef, Volkan, Diego, Nani, Fernandao
Manager: Vitor Pereira