Zlatan Ibrahimovic will make his unofficial debut for the Red Devils in his home country after joining the club from French giants PSG over the summer.
United boss Jose Mourinho will be familiar with a few Galatasaray players especially Wesley Sneijder who was part of his Inter Milan side that won the treble together – UEFA Champions League, Serie A and Italian Cup.
The experienced playmaker will start for Galatasaray but the Lions will be without Germany international Lukas Podolski as well as Umut Bulut, Olcan Adın, Tarık Çamdal and Endoğan Adili.
Manchester United v Galatasaray
Kick-off: 18: 30 GMT
Manchester United confirmed line-up: De Gea, Valencia, Baily, Blind, Shaw, Schneiderlin, Ander, Mkhitaryan, Rooney, Martial, Ibrahimovic
Manger: Jose Mourinho
Galatasaray probable line-up: Muslera, Linnes, Chedjou, Hakan Balta, Carole, Selcuk, Dzemaili, Bruma, Sneijder, Sinan Gümüş, Yasin Öztekin
Manager: Jan Olde Riekerink