Felipe Melo and Semih Kaya are both doubts for the Gaziantepspor games according to Galatasaray manager Hamza Hamzaoğlu.
“Semih and Melo are still doubts, they have been working with the team but they are not 100 percent yet, both will be game time decisions,” Hamzaoğlu was quoted as saying by Eurosport TR.
Kaya picked up an injury in the International Royal Cup friendly tournament during the winter break and has only just returned to training.
The Lions have dropped eight points following Melo picking up an injury last month culminating with the 2-1 loss against Trabzonspor at the Avni Aker stadium.
Galatasaray have lost against rivals Fenerbahçe and drew against Başakşehirspor. The Istanbul giants have won their four other games without the Brazilian midfielder.
Melo joined Galatasaray on a permanent deal from Juventus worth £3 million last summer after playing the previous two seasons on loan at the Lions.
The Brazilian midfielder has scored one goal in 22 appearances for Galatasaray in all competitors this season.