The Yellow Canaries are undefeated at home this season but will be taking on the leagues best performing defensive side in Kasimpasa.
The Istanbul minnows have conceded just 18 times this season and on-loan Chelsea defender Kenneth Omeruo has played a major role in contributing to that record.
The Nigerian international is expected to start for Kasimpasa but Fenerbahce will be missing two key defensive players in Mehmet Topal and Josef de Souza due to injury. Ozan Tufan and Diego are expected to fill in for the missing defensive midfielders but will offer a more attacking flavour as both are more offensively minded.
On-loan Liverpool winger Lazar Markovic will also be out for Fenerbahce due to injury.
Fenerbahce v Kasimpasa
Stadium: Sukru Saracoglu
Kick-Off: 18:00 GMT
Manager: Vitor Pereira
Kasimpasa: Ramazan, Veysel, Titi, Omeruo, Vigneau, Castro, Pavelka, Tunay, Hakan, Adem, Eren (Malki)
Manager: Riza Calimba