The Istanbul derby pits league leaders Beşiktaş against second placed Fenerbahçe. A victory for the Black Eagles would move them four points ahead of their cross-city rivals.
On-loan Liverpool winger has failed to recover in time for the derby and will be sidelined along with Ba for the Yellow Canaries.
Beşiktaş star Gökhan Töre has recovered but failed a late fitness test and will start on the bench.
Alper Potuk has been given the nod ahead of Nani and will be joined by fellow Turkish intentional on the other flank.
Referee: Cüneyt Çakır
Kick-Off: 18:00 GMT
Fenerbahce: Volkan, Gökhan, Alves, Kjaer, Caner, Josef, Mehmet Topal, Diego, Alper Potuk, Volkan Şen, van Persie
Manager: Vitor Pereira
Besiktas: Tolga, Beck, Alexis, Marcelo, İsmail, Atiba, Oğuzhan, Sosa, Quaresma, Olcay, Gomez
Subs: Boyko, Töre, Tosic, Kurtuluş, Arslan, Uysal, Tosun
Manager: Şenol Güneş