Liverpool take on Swansea City at the Liberty stadium having gone 12 games without a defeat in the Premier League.
The Reds are currently fifth in the league on 51 points but will close the gap with fourth placed Manchester United to just two points with a win against Swansea.
Swansea are currently in 9th place with 40 points from 28 games.
Emre Can will make his 30th appearances for the Reds against Swansea. The 21-year-old will start in the back-three alongside Martin Skrtel and Sakho.
Liverpool have not lost a Premier League game in which Can has started in defence this season.
Swansea City – Liverpool
Stadium: Liberty Stadium
Kick-Off: 20:00 GMT
Swansea: Fabianski, Naughton, Amat, Williams (capt), Taylor, Ki, Cork, Shelvey, Sigurdsson, Routledge, Gomis
Subs: Tremmel, Rangel, Britton, Dyer, Emnes, Montero, Oliviera
Manager: Gary Monk
Liverpool: Mignolet, Can, Skrtel, Sakho, Allen, Henderson, Lallana, Moreno, Coutinho, Sterling, Sturridge.
Subs: Jones, Johnson, Toure, Lovren, Gerrard, Lambert, Markovic.
Manager: Brendan Rodgers