On-loan Chelsea winger Marko Marin will make his first start for Trabzonspor while Okay Yokuşlu makes his return to the team after recovering from injury.
N’Doye has been given the nod ahead of last weeks goalscorer Oscar Cardozo.
Manchester City on-loan defender Jason Denayer will make his Super League debut for Galatasaray. The 20-year-old will be deployed as a right-back after an impressive performance against Atletico Madrid in the Champions League midweek.
Bilal Kısa will replace the suspended Selçuk Inan while Jose Rodriguez will start ahead of Emre Çolak who had a poor game against Atleti.
Trabzonspor are currently joint first in the Super League alongside Fenerbahçe on 10 points while Galatasaray trail in 11th place on just five points.
TRABZONSPOR – GALATASARAY
Stadium: Avni Aker
Referee: Cüneyt Çakır
Trabzonspor: Onur, Cavanda, Mustafa Yumlu, Douglas, Constant, Okay, MBia, Marko Marin, Özer, Erkan Zengin, NDoye
Manager: Shota Arveladez
Galatasaray: Muslera, Denayer, Semih, Hakan Balta, Carole, Rodriguez, Bilal, Yasin, Sneijder, Podolski, Burak
Manager: Hamza Hamzaoğlu