The 21-year-old’s exquisite pass with the outside of his foot set up Liverpool’s and Daniel Sturridge’s second goal.
England international Sturridge found the back of the net twice in the first half while Derek Origi scored a hat-trick. Jordon Ibe scored Liverpool’s remaining goal.
Can has one assist and one goal for Liverpool in 21 appearances this season.
Unfortunately Can picked up a yellow card in the second half meaning he will be suspended for this weekends Premier League clash with Newcastle United.
Southampton 1 – 5 Liverpool
Stadium: St Mary’s Stadium
Southampton starting line-up: Stkelenburg, Cedrid, Clasie, Davis, Mane, Tadic, Wanyama. Van Jikj, Pelle, Bertrand, Caulker
Subs: Gazzaniga, Yoshida, Long, Romeu, Martina, Ward-Prowse, Juanmi
Liverpool starting line-up: Bogdan, Randall, Skrtel, Lovren, Moreno, Can, Lucas, Allen, Lallana, Origi, Sturridge
Subs: Mignolet, Smith, Milner, Benteke, Firmino, Henderson, Ibe