Bilic is no stranger to the Premier League having enjoyed stints at West Ham and Everton as a player but this was his first game coaching a side in the league.
Jack Wilshere, Flamini and Rosicky, striker Danny Welbeck and Alexis Sanchez all missed the game for Arsenal but West Ham were also without first-team strikers including Andy Carroll.
Bilic developed a reputation as a manager capable of taking on Premier League giants last season during his time in charge of Besiktas.
In fact Besiktas pushed Arsenal to the wire in the Champions League play-off stage last season losing out 1-0 on aggregate.
Bilic achieved cult status among the Besiktas faithful despite failing to win silverware during his time in Turkey.